SOD2 Mediates Amifostine-Induced Protection against Glutamate in PC12 Cells

Background. Cytoprotectant amifostine attenuates radiation-induced oxidative injury by increasing intracellular manganese superoxide dismutase (SOD2) in peripheral tissue. However, whether amifostine could protect neuronal cells against oxidative injury has not been reported. The purpose of this stu...

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Bibliographic Details
Main Authors: Ji Jia, Lei Zhang, Xiaolei Shi, Mingchun Wu, Xiang Zhou, Xiaonan Liu, Tingting Huo
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2016/4202437