Effective noninvasive zygosity determination by maternal plasma target region sequencing.

Effective noninvasive zygosity determination by maternal plasma target region sequencing.

BACKGROUND: Currently very few noninvasive molecular genetic approaches are available to determine zygosity for twin pregnancies in clinical laboratories. This study aimed to develop a novel method to determine zygosity by using maternal plasma target region sequencing. METHODS: We constructed a sta...

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Bibliographic Details
Main Authors: Jing Zheng, Chenming Xu, Jing Guo, Yuan Wei, Huijuan Ge, Xuchao Li, Chunlei Zhang, Haojun Jiang, Ling Pan, Weiping Tang, Weiwei Xie, Hongyun Zhang, Yangyu Zhao, Fuman Jiang, Shengpei Chen, Wei Wang, Xun Xu, Fang Chen, Hefeng Huang, Hui Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3677919?pdf=render

Internet

http://europepmc.org/articles/PMC3677919?pdf=render

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