FDG PET Parkinson’s disease-related pattern as a biomarker for clinical trials in early stage disease

Background: The development of therapeutic interventions for Parkinson disease (PD) is challenged by disease complexity and subjectivity of symptom evaluation. A Parkinson's Disease Related Pattern (PDRP) of glucose metabolism via fluorodeoxyglucose positron emission tomography (FDG-PET) has be...

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Bibliographic Details
Main Authors: Dawn C. Matthews, Hedva Lerman, Ana Lukic, Randolph D. Andrews, Anat Mirelman, Miles N. Wernick, Nir Giladi, Stephen C. Strother, Karleyton C. Evans, Jesse M. Cedarbaum, Einat Even-Sapir
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:NeuroImage: Clinical
Online Access:http://www.sciencedirect.com/science/article/pii/S221315821830247X