MYB elongation is regulated by the nucleic acid binding of NFκB p50 to the intronic stem-loop region.

MYB transcriptional elongation is regulated by an attenuator sequence within intron 1 that has been proposed to encode a RNA stem loop (SLR) followed by a polyU tract. We report that NFκBp50 can bind the SLR polyU RNA and promote MYB transcriptional elongation together with NFκBp65. We identified a...

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Bibliographic Details
Main Authors: Lloyd A Pereira, Honor J Hugo, Jordane Malaterre, Xu Huiling, Secondo Sonza, Alina Cures, Damian F J Purcell, Paul A Ramsland, Steven Gerondakis, Thomas J Gonda, Robert G Ramsay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4390348?pdf=render