Molecular profiles of Quadriceps muscle in <it>myostatin</it>-null mice reveal PI3K and apoptotic pathways as myostatin targets
<p>Abstract</p> <p>Background</p> <p>Myostatin (MSTN), a member of the TGF-β superfamily, has been identified as a negative regulator of skeletal muscle mass. Inactivating mutations in the MSTN gene are responsible for the development of a hypermuscular phenotype. In th...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2009-04-01
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| Series: | BMC Genomics |
| Online Access: | http://www.biomedcentral.com/1471-2164/10/196 |