Exploration of C–H and N–H-bond functionalization towards 1-(1,2-diarylindol-3-yl)tetrahydroisoquinolines

Exploration of C–H and N–H-bond functionalization towards 1-(1,2-diarylindol-3-yl)tetrahydroisoquinolines

The synthesis of 1,2,3-trisubstituted indoles was investigated. More specifically, straightforward synthetic routes towards 1-(1,2-diarylindol-3-yl)-N-PG-THIQs (PG = protecting group, THIQ = tetrahydroisoquinoline) employing transition metal-catalyzed C–H and N–H-bond functionalization were explored...

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Bibliographic Details
Main Authors: Michael Ghobrial, Marko D. Mihovilovic, Michael Schnürch
Format: Article
Language:English
Published: Beilstein-Institut 2014-09-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Buchwald–Hartwig coupling
C–C coupling
C–H functionalization
iron catalysis
regioselective arylation
Online Access:https://doi.org/10.3762/bjoc.10.226

Internet

https://doi.org/10.3762/bjoc.10.226

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