Biomarker-guided trials: Challenges in practice

Biomarker-guided trials have drawn considerable attention as they promise to lead to improvements in the benefit-risk ratio of treatments and enhanced opportunities for drug development. A variety of such designs have been proposed in the literature, many of which have been adopted in practice.Imple...

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Bibliographic Details
Main Authors: M. Antoniou, R. Kolamunnage-Dona, J. Wason, R. Bathia, C. Billingham, J.M. Bliss, L.C. Brown, A. Gillman, J. Paul, A.L. Jorgensen
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Contemporary Clinical Trials Communications
Online Access:http://www.sciencedirect.com/science/article/pii/S2451865419302558