Differential regulation of hypoxanthine and xanthine by obesity in a general population

Differential regulation of hypoxanthine and xanthine by obesity in a general population

Abstract Aims/Introduction Uric acid is synthesized by oxidation of hypoxanthine and xanthine using a catalyzing enzyme, xanthine oxidoreductase (XOR), which can be a source of reactive oxygen species. Plasma XOR activity is a metabolic biomarker associated with obesity, hyperuricemia, liver dysfunc...

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Bibliographic Details
Main Authors: Masato Furuhashi, Masayuki Koyama, Yukimura Higashiura, Takayo Murase, Takashi Nakamura, Megumi Matsumoto, Akiko Sakai, Hirofumi Ohnishi, Marenao Tanaka, Shigeyuki Saitoh, Norihito Moniwa, Kazuaki Shimamoto, Tetsuji Miura
Format: Article
Language:English
Published: Wiley 2020-07-01
Series:Journal of Diabetes Investigation
Subjects:
Purine metabolism
Salvage pathway
Xanthine oxidoreductase
Online Access:https://doi.org/10.1111/jdi.13207

Internet

https://doi.org/10.1111/jdi.13207

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