A chitosan-based cascade-responsive drug delivery system for triple-negative breast cancer therapy

A chitosan-based cascade-responsive drug delivery system for triple-negative breast cancer therapy

Abstract Background It is extremely difficult to develop targeted treatments for triple-negative breast (TNB) cancer, because these cells do not express any of the key biomarkers usually exploited for this goal. Results In this work, we develop a solution in the form of a cascade responsive nanoplat...

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Bibliographic Details
Main Authors: Shiwei Niu, Gareth R. Williams, Jianrong Wu, Junzi Wu, Xuejing Zhang, Xia Chen, Shude Li, Jianlin Jiao, Li-Min Zhu
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Journal of Nanobiotechnology
Subjects:
Chitosan
Doxorubicin
Triple-negative breast
Cascade responsive
Cell penetrating peptide
Online Access:http://link.springer.com/article/10.1186/s12951-019-0529-4

Internet

http://link.springer.com/article/10.1186/s12951-019-0529-4

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