Anti-schistosomal drugs: observations on the mechanism of drug resistance to hycanthone, and on the involvement of host antibodies in the mode of action of praziquantel
This paper reports recent observations from our laboratory dealing with the anti-schistosome drugs hycanthone (HC) and praziquantel (PZQ). In particular, we discuss a laboratory model of drug resistance to HC in Schistosoma mansoni and show that drug sensitive and resistant lines of the parasite can...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Instituto Oswaldo Cruz, Ministério da Saúde
1987-01-01
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| Series: | Memórias do Instituto Oswaldo Cruz. |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761987000800027 |