The KOUNCIL Consortium: From Genetic Defects to Therapeutic Development for Nephronophthisis

The KOUNCIL Consortium: From Genetic Defects to Therapeutic Development for Nephronophthisis

Nephronophthisis (NPH) is the most common monogenic cause of renal failure in children. Treatment options are limited to dialysis and transplantation. Therapeutics to significantly delay or prevent end-stage renal disease (ESRD) in children are currently not available. In the Dutch-Anglo KOUNCIL (Ki...

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Bibliographic Details
Main Authors: Kirsten Y. Renkema, Rachel H. Giles, Marc R. Lilien, Philip L. Beales, Ronald Roepman, Machteld M. Oud, Heleen H. Arts, Nine V. A. M. Knoers
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Pediatrics
Subjects:
cilia
pediatric kidney disease
nephronophthisis
renal ciliopathy
genetics
Online Access:http://journal.frontiersin.org/article/10.3389/fped.2018.00131/full

Internet

http://journal.frontiersin.org/article/10.3389/fped.2018.00131/full

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