Modulation of pluripotency in the porcine embryo and iPS cells.

The establishment of the pluripotent ICM during early mammalian development is characterized by the differential expression of the transcription factors NANOG and GATA4/6, indicative of the epiblast and hypoblast, respectively. Differences in the mechanisms regulating the segregation of these lineag...

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Bibliographic Details
Main Authors: Aida Rodríguez, Cinzia Allegrucci, Ramiro Alberio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3493503?pdf=render