Targeted deletion of neuropeptide Y (NPY) modulates experimental colitis.

Targeted deletion of neuropeptide Y (NPY) modulates experimental colitis.

Neurogenic inflammation plays a major role in the pathogenesis of inflammatory bowel disease (IBD). We examined the role of neuropeptide Y (NPY) and neuronal nitric oxide synthase (nNOS) in modulating colitis.Colitis was induced by administration of dextran sodium sulphate (3% DSS) or streptomycin p...

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Bibliographic Details
Main Authors: Bindu Chandrasekharan, Vanitha Bala, Vasantha L Kolachala, Matam Vijay-Kumar, Dean Jones, Andrew T Gewirtz, Shanthi V Sitaraman, Shanthi Srinivasan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2561053?pdf=render

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http://europepmc.org/articles/PMC2561053?pdf=render

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