Role of VEGFR2 in Mediating Endoplasmic Reticulum Stress Under Glucose Deprivation and Determining Cell Death, Oxidative Stress, and Inflammatory Factor Expression

Role of VEGFR2 in Mediating Endoplasmic Reticulum Stress Under Glucose Deprivation and Determining Cell Death, Oxidative Stress, and Inflammatory Factor Expression

Retinal pigment epithelium (RPE), a postmitotic monolayer located between the neuroretina and choroid, supports the retina and is closely associated with vision loss diseases such as age-related macular degeneration (AMD) upon dysfunction. Although environmental stresses are known to play critical r...

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Bibliographic Details
Main Authors: Bohan Xu, Linbin Zhou, Qishan Chen, Jianing Zhang, Lijuan Huang, Shasha Wang, Zhimin Ye, Xiangrong Ren, Yu Cai, Lasse Dahl Jensen, Weirong Chen, Xuri Li, Rong Ju
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
eye diseases
visual development
translational vision science
advanced technology
VEGFR2
ER stress
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.631413/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.631413/full

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