Telomere length as a quantitative trait: genome-wide survey and genetic mapping of telomere length-control genes in yeast.

Telomere length-variation in deletion strains of Saccharomyces cerevisiae was used to identify genes and pathways that regulate telomere length. We found 72 genes that when deleted confer short telomeres, and 80 genes that confer long telomeres relative to those of wild-type yeast. Among identified...

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Bibliographic Details
Main Authors: Tonibelle Gatbonton, Maria Imbesi, Melisa Nelson, Joshua M Akey, Douglas M Ruderfer, Leonid Kruglyak, Julian A Simon, Antonio Bedalov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1401499?pdf=render