Medullospheres from DAOY, UW228 and ONS-76 cells: increased stem cell population and proteomic modifications.

BACKGROUND: Medulloblastoma (MB) is an aggressive pediatric tumor of the Central Nervous System (CNS) usually treated according to a refined risk stratification. The study of cancer stem cells (CSC) in MB is a promising approach aimed at finding new treatment strategies. METHODOLOGY/PRINCIPAL FINDIN...

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Bibliographic Details
Main Authors: Cristina Zanini, Elisabetta Ercole, Giorgia Mandili, Roberta Salaroli, Alice Poli, Cristiano Renna, Valentina Papa, Giovanna Cenacchi, Marco Forni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3663798?pdf=render