Pure Large Nested Variant of Urothelial Carcinoma (LNUC) Is the Prototype of an <i>FGFR3</i> Mutated Aggressive Urothelial Carcinoma with Luminal-Papillary Phenotype

Pure Large Nested Variant of Urothelial Carcinoma (LNUC) Is the Prototype of an <i>FGFR3</i> Mutated Aggressive Urothelial Carcinoma with Luminal-Papillary Phenotype

Since 2016, large nested urothelial carcinoma (LNUC) has been included within the WHO classification of urothelial tumors. Limited reports with mainly small case series have confirmed the malignant behavior of LNUC despite its bland morphological appearance. We evaluated, for the first time, markers...

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Bibliographic Details
Main Authors: Veronika Weyerer, Markus Eckstein, Eva Compérat, Hendrik Juette, Nadine T. Gaisa, Yves Allory, Robert Stöhr, Bernd Wullich, Morgan Rouprêt, Arndt Hartmann, Simone Bertz
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
urothelial carcinoma
large nested variant
lnuc
<i>fgfr3</i> mutation
luminal subtype
Online Access:https://www.mdpi.com/2072-6694/12/3/763

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https://www.mdpi.com/2072-6694/12/3/763

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