Detection of oncogenic mutations in paired circulating tumor DNA and circulating tumor cells in patients with hepatocellular carcinoma

Detection of oncogenic mutations in paired circulating tumor DNA and circulating tumor cells in patients with hepatocellular carcinoma

Background and aims: Circulating tumor cells (CTCs) or circulating tumor DNA (ctDNA) may be used for diagnostic or prognostic purposes in patients with hepatocellular carcinoma (HCC). We aim to determine whether CTCs or ctDNA are suitable to determine oncogenic mutations in HCC patients. Methods: Tw...

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Bibliographic Details
Main Authors: Zhouhong Ge, Jean C.A. Helmijr, Maurice P.H.M. Jansen, Patrick P.C. Boor, Lisanne Noordam, Maikel Peppelenbosch, Jaap Kwekkeboom, Jaco Kraan, Dave Sprengers
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Translational Oncology
Subjects:
Circulating tumor DNA
Circulating tumor cells
TERT promoter mutations
Macrovascular invasion
Hepatocellular carcinoma
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523321000656

Internet

http://www.sciencedirect.com/science/article/pii/S1936523321000656

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