Acute oxidative stress and systemic Nrf2 activation by the ketogenic diet
The mechanisms underlying the efficacy of the ketogenic diet (KD) remain unknown. Recently, we showed that the KD increased glutathione (GSH) biosynthesis. Since the NF E2-related factor 2 (Nrf2) transcription factor is a primary responder to cellular stress and can upregulate GSH biosynthesis, we a...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2010-10-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996110001920 |