Involvement of HB-EGF/Ascl1/Lin28a Genes in Dedifferentiation of Adult Mammalian Müller Glia

Involvement of HB-EGF/Ascl1/Lin28a Genes in Dedifferentiation of Adult Mammalian Müller Glia

Previous studies from this lab have determined that dedifferentiation of Müller glia occurs after eye drop application of an α7 nicotinic acetylcholine receptor (nAChR) agonist, PNU-282987, to the adult rodent eye. PNU-282987 acts on α7 nAChRs on retinal pigment epithelial cells to stimulate product...

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Bibliographic Details
Main Authors: Megan L. Stanchfield, Sarah E. Webster, Mark K. Webster, Cindy L. Linn
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Molecular Biosciences
Subjects:
mammalian retinal regeneration
Müller glia
dedifferentiation
retinal pigment epithelium
α7 nicotinic acetylcholine receptor agonist
Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2020.00200/full

Internet

https://www.frontiersin.org/article/10.3389/fmolb.2020.00200/full

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