Incorporating biological pathways via a Markov random field model in genome-wide association studies.
Genome-wide association studies (GWAS) examine a large number of markers across the genome to identify associations between genetic variants and disease. Most published studies examine only single markers, which may be less informative than considering multiple markers and multiple genes jointly bec...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2011-04-01
|
| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC3072362?pdf=render |