Synthesis of Chlorotoxin by Native Chemical Ligation

Synthesis of Chlorotoxin by Native Chemical Ligation

Chlorotoxin (CLTX) is a neurotoxin found in the venom of the Israeli scorpion, Leirius quinquestriatus. It contains 36-amino acids with four disulfide bonds and inhibits low-conductance chloride channels. CLTX also binds to matrix metalloproteinase-2 (MMP-2) selectively. The synthesis of chlorotoxi...

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Bibliographic Details
Main Authors: Ulvi Karaca, Seçkin Kesici, Salih Özçubukçu
Format: Article
Language:English
Published: Turkish Chemical Society 2018-01-01
Series:Journal of the Turkish Chemical Society, Section A: Chemistry
Subjects:
chlorotoxin
solid phase peptide synthesis
Online Access:http://dergipark.gov.tr/jotcsa/issue/33408/408517

Internet

http://dergipark.gov.tr/jotcsa/issue/33408/408517

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