Synthesis of Chlorotoxin by Native Chemical Ligation
Chlorotoxin (CLTX) is a neurotoxin found in the venom of the Israeli scorpion, Leirius quinquestriatus. It contains 36-amino acids with four disulfide bonds and inhibits low-conductance chloride channels. CLTX also binds to matrix metalloproteinase-2 (MMP-2) selectively. The synthesis of chlorotoxi...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Turkish Chemical Society
2018-01-01
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Series: | Journal of the Turkish Chemical Society, Section A: Chemistry |
Subjects: | |
Online Access: | http://dergipark.gov.tr/jotcsa/issue/33408/408517 |