Might Fibroblasts from Patients with Alzheimer’s Disease Reflect the Brain Pathology? A Focus on the Increased Phosphorylation of Amyloid Precursor Protein Tyr<sub>682</sub> Residue

Might Fibroblasts from Patients with Alzheimer’s Disease Reflect the Brain Pathology? A Focus on the Increased Phosphorylation of Amyloid Precursor Protein Tyr<sub>682</sub> Residue

Alzheimer’s disease (AD) is a devastating neurodegenerative disorder with no cure and no effective diagnostic criteria. The greatest challenge in effectively treating AD is identifying biomarkers specific for each patient when neurodegenerative processes have not yet begun, an outcome that would all...

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Bibliographic Details
Main Authors: Filomena Iannuzzi, Vincenza Frisardi, Lucio Annunziato, Carmela Matrone
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Brain Sciences
Subjects:
Alzheimer’s disease
amyloid precursor protein
Tyr682 residue
YENPTY motif
Fyn tyrosine kinase
amyloid beta
Online Access:https://www.mdpi.com/2076-3425/11/1/103

Internet

https://www.mdpi.com/2076-3425/11/1/103

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