Polar Infection of Echovirus-30 Causes Differential Barrier Affection and Gene Regulation at the Blood–Cerebrospinal Fluid Barrier

Polar Infection of Echovirus-30 Causes Differential Barrier Affection and Gene Regulation at the Blood–Cerebrospinal Fluid Barrier

Echovirus-30 (E-30) is responsible for the extensive global outbreaks of meningitis in children. To gain access to the central nervous system, E-30 first has to cross the epithelial blood–cerebrospinal fluid barrier. Several meningitis causing bacteria preferentially infect human choroid plexus papi...

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Bibliographic Details
Main Authors: Marie Wiatr, Ricardo Figueiredo, Carolin Stump-Guthier, Peter Winter, Hiroshi Ishikawa, Ortwin Adams, Christian Schwerk, Horst Schroten, Henriette Rudolph, Tobias Tenenbaum
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
blood–cerebrospinal fluid barrier
Echovirus-30
meningitis
polarity
MACE RNA sequencing
Online Access:https://www.mdpi.com/1422-0067/21/17/6268

Internet

https://www.mdpi.com/1422-0067/21/17/6268

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