Antagonizing S1P<sub>3</sub> Receptor with Cell-Penetrating Pepducins in Skeletal Muscle Fibrosis

Antagonizing S1P<sub>3</sub> Receptor with Cell-Penetrating Pepducins in Skeletal Muscle Fibrosis

S1P is the final product of sphingolipid metabolism, which interacts with five widely expressed GPCRs (S1P<sub>1-5</sub>). Increasing numbers of studies have indicated the importance of S1P<sub>3</sub> in various pathophysiological processes. Recently, we have identified a pe...

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Bibliographic Details
Main Authors: Angela Corvino, Ida Cerqua, Alessandra Lo Bianco, Giuseppe Caliendo, Ferdinando Fiorino, Francesco Frecentese, Elisa Magli, Elena Morelli, Elisa Perissutti, Vincenzo Santagada, Giuseppe Cirino, Elisabetta Granato, Fiorentina Roviezzo, Elisa Puliti, Caterina Bernacchioni, Antonio Lavecchia, Chiara Donati, Beatrice Severino
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
sphingosine-1-phosphate
S1P<sub>3</sub> receptor antagonist
skeletal muscle fibrosis
molecular dynamics simulations
Online Access:https://www.mdpi.com/1422-0067/22/16/8861

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https://www.mdpi.com/1422-0067/22/16/8861

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