NS4/5 mutations enhance flavivirus Bamaga virus infectivity and pathogenicity in vitro and in vivo.

NS4/5 mutations enhance flavivirus Bamaga virus infectivity and pathogenicity in vitro and in vivo.

Flaviviruses such as yellow fever, dengue or Zika viruses are responsible for significant human and veterinary diseases worldwide. These viruses contain an RNA genome, prone to mutations, which enhances their potential to emerge as pathogens. Bamaga virus (BgV) is a mosquito-borne flavivirus in the...

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Bibliographic Details
Main Authors: Agathe M G Colmant, Helle Bielefeldt-Ohmann, Laura J Vet, Caitlin A O'Brien, Richard A Bowen, Airn E Hartwig, Steven Davis, Thisun B H Piyasena, Gervais Habarugira, Jessica J Harrison, Jody Hobson-Peters, Roy A Hall
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008166

Internet

https://doi.org/10.1371/journal.pntd.0008166

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