Efficacy of a Protein Vaccine and a Conjugate Vaccine Against Co-colonization with Vaccine-type and Non-vaccine Type Pneumococci in Mice

Widespread use of pneumococcal conjugate vaccines (PCVs) has led to substitution of vaccine-type (VT) strains by non-vaccine type (NVT) strains in nasopharyngeal carriage. We compared the efficacy of PCV13 and a nasal protein formulation containing pneumococcal surface protein A (PspA) adjuvanted wi...

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Bibliographic Details
Main Authors: Gabriela BC Colichio, Giuliana S Oliveira, Tasson C Rodrigues, Maria Leonor S Oliveira, Eliane N Miyaji
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/9/4/278