RNA interference mediated inhibition of dengue virus multiplication and entry in HepG2 cells.

BACKGROUND: Dengue virus-host cell interaction initiates when the virus binds to the attachment receptors followed by endocytic internalization of the virus particle. Successful entry into the cell is necessary for infection initiation. Currently, there is no protective vaccine or antiviral treatmen...

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Bibliographic Details
Main Authors: Mohammed Abdelfatah Alhoot, Seok Mui Wang, Shamala Devi Sekaran
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3311579?pdf=render