Human pancreatic cancer-associated stellate cells remain activated after in vivo chemoradiation

Human pancreatic cancer-associated stellate cells remain activated after in vivo chemoradiation

Pancreatic ductal adenocarcinoma (PDAC) is characterized by an extensive fibrotic reaction or desmoplasia and complex involvement of the surrounding tumor microenvironment. Pancreatic stellate cells are a key mediator of the pancreatic matrix and they promote progression and invasion of pancreatic c...

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Bibliographic Details
Main Authors: Marina Carla Cabrera, Estifanos eTilahun, Rebecca eNakles, Edgar eDiaz-Cruz, Aline eCharabaty, Simeng eSuy, Patrick eJackson, Lisa eLey, Rebecca eSlack, Reena eJha, Sean P Collins, Nadim eHaddad, Bhaskar V.S. Kallakury, Timm eSchroeder, Michael J Pishvaian, Priscilla A Furth
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Oncology
Subjects:
Chemoradiotherapy
Radiation
chemotherapy
stellate cells
gastrointestinal
Pancreatic Cancer
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00102/full

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http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00102/full

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