Inhibitory Effect of Cudratrixanthone U on RANKL-Induced Osteoclast Differentiation and Function in Macrophages and BMM Cells

Inhibitory Effect of Cudratrixanthone U on RANKL-Induced Osteoclast Differentiation and Function in Macrophages and BMM Cells

Cudratrixanthone U (CTU) is a prenylated xanthone compound isolated from Maclura tricuspidata Bureau (Moraceae). Prenylated xanthones have been reported to exhibit a variety of biological activities. However, the effects of prenylated xanthone on osteoclast differentiation and function are still unc...

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Bibliographic Details
Main Authors: Eun-Nam Kim, Jaeyoung Kwon, Hyun-Su Lee, Sooyeun Lee, Dongho Lee, Gil-Saeng Jeong
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Pharmacology
Subjects:
Cudratrixanthone U
TRAF6
TAK-1
RANKL
CCL4
osteoclast
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.01048/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.01048/full

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