Fenofibrate Nanocrystal Composite Microparticles for Intestine-Specific Oral Drug Delivery System

Fenofibrate Nanocrystal Composite Microparticles for Intestine-Specific Oral Drug Delivery System

Hydrophobic drug nanocrystals (NCs) manufactured by particle engineering have been extensively investigated for enhanced oral bioavailability and therapeutic effectiveness. However, there are significant drawbacks, including fast dissolution of the nanocrystals in the gastric environment, leading to...

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Bibliographic Details
Main Authors: Bhavesh D. Kevadiya, Liang Chen, Lu Zhang, Midhun B. Thomas, Rajesh N. Davé
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Pharmaceuticals
Subjects:
bioavailability
fenofibrate
media milling
nanocrystals
intestine-specific delivery
composites spherical microparticles
Online Access:https://www.mdpi.com/1424-8247/12/3/109

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https://www.mdpi.com/1424-8247/12/3/109

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