GLT-1-Dependent Disruption of CNS Glutamate Homeostasis and Neuronal Function by the Protozoan Parasite Toxoplasma gondii.

GLT-1-Dependent Disruption of CNS Glutamate Homeostasis and Neuronal Function by the Protozoan Parasite Toxoplasma gondii.

The immune privileged nature of the CNS can make it vulnerable to chronic and latent infections. Little is known about the effects of lifelong brain infections, and thus inflammation, on the neurological health of the host. Toxoplasma gondii is a parasite that can infect any mammalian nucleated cell...

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Bibliographic Details
Main Authors: Clément N David, Elma S Frias, Jenny I Szu, Philip A Vieira, Jacqueline A Hubbard, Jonathan Lovelace, Marena Michael, Danielle Worth, Kathryn E McGovern, Iryna M Ethell, B Glenn Stanley, Edward Korzus, Todd A Fiacco, Devin K Binder, Emma H Wilson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-06-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4900626?pdf=render

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http://europepmc.org/articles/PMC4900626?pdf=render

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