Osteogenic differentiation as a result of BMP-2 plasmid DNA based gene therapy in vitro and in vivo

Bone regeneration is one of the major focus points in the field of regenerative medicine. A well-known stimulus of bone formation is bone morphogenetic protein-2 (BMP-2), which has already been extensively used in clinical applications. We investigated the possibility of achieving osteogenic differe...

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Bibliographic Details
Main Authors: F Wegman, A Bijenhof, L Schuijff, FC Öner, WJA Dhert, J Alblas
Format: Article
Language:English
Published: AO Research Institute Davos 2011-03-01
Series:European Cells & Materials
Subjects:
Online Access:http://www.ecmjournal.org/journal/papers/vol021/pdf/v021a18.pdf