Synthesis and Biological Evaluation of New 4,5-Disubstituted-Thiazolyl Amides, Derivatives of 4-Hydroxy-Piperidine or of 4-N-Methyl Piperazine

4,5-disubstituted-thizolyl amides, derivatives of 4-hydroxy-piperidine and of 4-N-methyl piperazine, were synthesized and tested as anti-inflammatory agents. Log P values were theoretically calculated and experimentally determined. These compounds were tested for antioxidant activity, as hydroxyl ra...

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Bibliographic Details
Main Authors: G. Soloupis, C. Chatziopoulos, D. Hadjipavlou-Litina, A. Geronikaki
Format: Article
Language:English
Published: MDPI AG 2003-06-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/8/6/472/