Insights into the pathogenesis of multiple system atrophy: focus on glial cytoplasmic inclusions

Insights into the pathogenesis of multiple system atrophy: focus on glial cytoplasmic inclusions

Abstract Multiple system atrophy (MSA) is a debilitating and fatal neurodegenerative disorder. The disease severity warrants urgent development of disease-modifying therapy, but the disease pathogenesis is still enigmatic. Neurodegeneration in MSA brains is preceded by the emergence of glial cytopla...

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Bibliographic Details
Main Authors: Seiji Kaji, Takakuni Maki, Tomoyuki Ishimoto, Hodaka Yamakado, Ryosuke Takahashi
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Translational Neurodegeneration
Subjects:
Multiple system atrophy
α-Synuclein
Glial cytoplasmic inclusion
Prion
Neurodegeneration
Oligodendrocyte
Online Access:http://link.springer.com/article/10.1186/s40035-020-0185-5

Internet

http://link.springer.com/article/10.1186/s40035-020-0185-5

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