Oligodendrocyte precursor cells support blood-brain barrier integrity via TGF-β signaling.

Oligodendrocyte precursor cells support blood-brain barrier integrity via TGF-β signaling.

Trophic coupling between cerebral endothelium and their neighboring cells is required for the development and maintenance of blood-brain barrier (BBB) function. Here we report that oligodendrocyte precursor cells (OPCs) secrete soluble factor TGF-β1 to support BBB integrity. Firstly, we prepared con...

Full description

Bibliographic Details
Main Authors: Ji Hae Seo, Takakuni Maki, Mitsuyo Maeda, Nobukazu Miyamoto, Anna C Liang, Kazuhide Hayakawa, Loc-Duyen D Pham, Fumihiko Suwa, Akihiko Taguchi, Tomohiro Matsuyama, Masafumi Ihara, Kyu-Won Kim, Eng H Lo, Ken Arai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4117639?pdf=render

Internet

http://europepmc.org/articles/PMC4117639?pdf=render

Similar Items