The Loss of HLA-F/KIR3DS1 Ligation Is Mediated by Hemoglobin Peptides

The human leukocyte antigen (HLA)-Ib molecule, HLA-F, is known as a CD4<sup>+</sup> T-cell protein and mediator of HIV progression. While HLA-Ia molecules do not have the chance to select and present viral peptides for immune recognition due to protein downregulation, HLA-F is upregulate...

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Bibliographic Details
Main Authors: Gia-Gia T. Hò, Wiebke Hiemisch, Andreas Pich, Georg M. N. Behrens, Rainer Blasczyk, Christina Bade-Doeding
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/21/8012