Overexpression of B7-H3 in α-SMA-Positive Fibroblasts Is Associated With Cancer Progression and Survival in Gastric Adenocarcinomas

Overexpression of B7-H3 in α-SMA-Positive Fibroblasts Is Associated With Cancer Progression and Survival in Gastric Adenocarcinomas

Background: B7-H3 promotes tumor immune escape and is highly expressed in tumor tissues. Stromal cells in tumors, including fibroblasts, play an important role in this process; however, the role of B7-H3 in tumor fibroblasts has not been fully clarified.Methods: We examined B7-H3, CD31, and alpha-sm...

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Bibliographic Details
Main Authors: Shenghua Zhan, Zhiju Liu, Min Zhang, Tianwei Guo, Qiuying Quan, Lili Huang, Lingchuan Guo, Lei Cao, Xueguang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Oncology
Subjects:
cancer-associated fibroblast
B7-H3
α-SMA
gastric adenocarcinoma
prognosis
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01466/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.01466/full

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