Monoterpenoids Induce Agonist-Specific Desensitization of Transient Receptor Potential Vanilloid-3 (TRPV3) ion Channels

Transient receptor potential vanilloid-3 (TRPV3) is a thermo-sensitive ion channel expressed in skin keratinocytes and in a variety of neural cells. It is activated by warmth as well as monoterpenoids including camphor, menthol, dihydrocarveol and 1,8-cineol. TRPV3 is described as a putative nocicep...

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Bibliographic Details
Main Authors: Muhammad Azhar Sherkheli, Heike Benecke, Julia Franca Doerner, Olaf Kletke, A. K. Vogt-Eisele, Guenter Gisselmann, Hanns Hatt
Format: Article
Language:English
Published: Canadian Society for Pharmaceutical Sciences 2009-04-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/5021