Cerebrospinal fluid antibodies to aquaporin-4 in neuromyelitis optica and related disorders: frequency, origin, and diagnostic relevance

Cerebrospinal fluid antibodies to aquaporin-4 in neuromyelitis optica and related disorders: frequency, origin, and diagnostic relevance

<p>Abstract</p> <p>Background</p> <p>In 70-80% of cases, neuromyelitis optica (NMO) is associated with highly specific serum auto-antibodies to aquaporin-4 (termed AQP4-Ab or NMO-IgG). Recent evidence strongly suggests that AQP4-Ab are directly involved in the immunopat...

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Bibliographic Details
Main Authors: Jarius Sven, Franciotta Diego, Paul Friedemann, Ruprecht Klemens, Bergamaschi Roberto, Rommer Paulus S, Reuss Reinhard, Probst Christian, Kristoferitsch Wolfgang, Wandinger Klaus, Wildemann Brigitte
Format: Article
Language:English
Published: BMC 2010-09-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/7/1/52

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http://www.jneuroinflammation.com/content/7/1/52

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