SEMG1/2 augment energy metabolism of tumor cells

Abstract SEMG1 and SEMG2 genes belong to the family of cancer-testis antigens (CTAs), whose expression normally is restricted to male germ cells but is often restored in various malignancies. High levels of SEMG1 and SEMG2 expression are detected in prostate, renal, and lung cancer as well as hemobl...

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Main Authors: Oleg Shuvalov, Alyona Kizenko, Alexey Petukhov, Olga Fedorova, Alexandra Daks, Andrew Bottrill, Anastasiya V. Snezhkina, Anna V. Kudryavtseva, Nikolai Barlev
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-020-03251-w