Helper-free Production of Laboratory Grade AAV and Purification by Iodixanol Density Gradient Centrifugation
Adeno-associated virus (AAV) is one of the most promising gene therapy vectors and is widely used as a gene delivery vehicle for basic research. As AAV continues to become the vector of choice, it is increasingly important for new researchers to have access to a simplified production and purificatio...
Main Authors: | Sean M. Crosson, Peter Dib, J. Kennon Smith, Sergei Zolotukhin |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-09-01
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Series: | Molecular Therapy: Methods & Clinical Development |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2329050118300470 |
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