Combinatorial Avidity Selection of Mosaic Landscape Phages Targeted at Breast Cancer Cells—An Alternative Mechanism of Directed Molecular Evolution

Low performance of actively targeted nanomedicines required revision of the traditional drug targeting paradigm and stimulated the development of novel phage-programmed, self-navigating drug delivery vehicles. In the proposed smart vehicles, targeting peptides, selected from phage libraries using tr...

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Bibliographic Details
Main Authors: Valery A. Petrenko, James W. Gillespie, Hai Xu, Tiffany O’Dell, Laura M. De Plano
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/11/9/785