Combinatorial Avidity Selection of Mosaic Landscape Phages Targeted at Breast Cancer Cells—An Alternative Mechanism of Directed Molecular Evolution
Low performance of actively targeted nanomedicines required revision of the traditional drug targeting paradigm and stimulated the development of novel phage-programmed, self-navigating drug delivery vehicles. In the proposed smart vehicles, targeting peptides, selected from phage libraries using tr...
Main Authors: | Valery A. Petrenko, James W. Gillespie, Hai Xu, Tiffany O’Dell, Laura M. De Plano |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-08-01
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Series: | Viruses |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4915/11/9/785 |
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