Computational Pipeline for the PGV-001 Neoantigen Vaccine Trial

Computational Pipeline for the PGV-001 Neoantigen Vaccine Trial

This paper describes the sequencing protocol and computational pipeline for the PGV-001 personalized vaccine trial. PGV-001 is a therapeutic peptide vaccine targeting neoantigens identified from patient tumor samples. Peptides are selected by a computational pipeline that identifies mutations from t...

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Bibliographic Details
Main Authors: Alex Rubinsteyn, Julia Kodysh, Isaac Hodes, Sebastien Mondet, Bulent Arman Aksoy, John P. Finnigan, Nina Bhardwaj, Jeffrey Hammerbacher
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Immunology
Subjects:
neoantigens
personalized vaccine
immunoinformatics
genomics
computational pipeline
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01807/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01807/full

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