A Novel Spot-Enhancement Anisotropic Diffusion Method for the Improvement of Segmentation in Two-dimensional Gel Electrophoresis Images, Based on the Watershed Transform Algorithm

Introduction Two-dimensional gel electrophoresis (2DGE) is a powerful technique in proteomics for protein separation. In this technique, spot segmentation is an essential stage, which can be challenging due to problems such as overlapping spots, streaks, artifacts and noise. Watershed transform is o...

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Bibliographic Details
Main Authors: Sina Shamekhi, Mohammad Hossein Miran Beygi, Bahareh Azarian, Ali Gooya
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2015-09-01
Series:Iranian Journal of Medical Physics
Subjects:
Online Access:http://ijmp.mums.ac.ir/article_6222_1a33385cb3708b2cfc422ae53f605809.pdf