PRDI-BF1 and PRDI-BF1β isoform expressions correlate with disease status in multiple myeloma patients

Human positive regulatory domain I binding factor 1 (PRDI-BF1 or BLIMP-1) is a transcription factor that acts as a master regulator and has crucial roles in the control of differentiation and in maintaining survival of plasma cells (PC). The PRDM1 gene, which codifies for PRDI-BF1, contains an alter...

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Bibliographic Details
Main Authors: Gabriele Buda, Francesca Guerrini, Sara Galimberti, Enrico Orciuolo, Simone Pacini, Elisa Mazzantini, Mario Petrini
Format: Article
Language:English
Published: PAGEPress Publications 2017-12-01
Series:Hematology Reports
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Online Access:http://www.pagepress.org/journals/index.php/hr/article/view/7201