Patterns of variation in cis-regulatory regions: examining evidence of purifying selection

Patterns of variation in cis-regulatory regions: examining evidence of purifying selection

Abstract Background With only 2 % of the human genome consisting of protein coding genes, functionality across the rest of the genome has been the subject of much debate. This has gained further impetus in recent years due to a rapidly growing catalogue of genomic elements, based primarily on bioche...

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Bibliographic Details
Main Authors: Thijessen Naidoo, Per Sjödin, Carina Schlebusch, Mattias Jakobsson
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Genomics
Subjects:
Regulatory regions
Purifying selection
Selection efficacy
Non-coding DNA
Functional elements
Population genetics
Online Access:http://link.springer.com/article/10.1186/s12864-017-4422-y

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http://link.springer.com/article/10.1186/s12864-017-4422-y

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