Axl Promotes Zika Virus Entry and Modulates the Antiviral State of Human Sertoli Cells

Axl Promotes Zika Virus Entry and Modulates the Antiviral State of Human Sertoli Cells

Recent Zika virus (ZIKV) outbreaks have identified sexual transmission as a new route of disease spread not reported for other flaviviruses. ZIKV crosses the blood-testis barrier and establishes infection in seminiferous tubules, the site for spermatozoa development. Currently, there are no therapie...

Full description

Bibliographic Details
Main Authors: Daniel P. Strange, Boonyanudh Jiyarom, Nima Pourhabibi Zarandi, Xuping Xie, Coleman Baker, Hooman Sadri-Ardekani, Pei-Yong Shi, Saguna Verma
Format: Article
Language:English
Published: American Society for Microbiology 2019-07-01
Series:mBio
Subjects:
axl receptor tyrosine kinase
sertoli cells
zika virus
interferon signaling
testes
testicular organoids
virus entry
Online Access:https://doi.org/10.1128/mBio.01372-19

Internet

https://doi.org/10.1128/mBio.01372-19

Similar Items