FOXN3 controls liver glucose metabolism by regulating gluconeogenic substrate selection

Abstract The FOXN3 gene locus is associated with fasting blood glucose levels in non‐diabetic human population genetic studies. The blood glucose‐modifying variation within this gene regulates the abundance of both FOXN3 protein and transcript in primary human hepatocytes, with the hyperglycemia ris...

Full description

Bibliographic Details
Main Authors: Santhosh Karanth, Bhagirath Chaurasia, Faith M. Bowman, Trevor S. Tippetts, William L. Holland, Scott A. Summers, Amnon Schlegel
Format: Article
Language:English
Published: Wiley 2019-09-01
Series:Physiological Reports
Subjects:
MYC
Online Access:https://doi.org/10.14814/phy2.14238