FOXN3 controls liver glucose metabolism by regulating gluconeogenic substrate selection
Abstract The FOXN3 gene locus is associated with fasting blood glucose levels in non‐diabetic human population genetic studies. The blood glucose‐modifying variation within this gene regulates the abundance of both FOXN3 protein and transcript in primary human hepatocytes, with the hyperglycemia ris...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2019-09-01
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Series: | Physiological Reports |
Subjects: | |
Online Access: | https://doi.org/10.14814/phy2.14238 |